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Nobuakira Takeda Selected Research

sarpogrelate

4/2008Antiplatelet therapy mitigates cardiac remodeling and dysfunction in congestive heart failure due to myocardial infarction.
1/2008Antiplatelet agents sarpogrelate and cilostazol affect experimentally-induced ventricular arrhythmias and mortality.
1/2004Therapeutic potentials of sarpogrelate in cardiovascular disease.
1/2002Blockade of 5-HT(2A) receptors by sarpogrelate protects the heart against myocardial infarction in rats.

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Nobuakira Takeda Research Topics

Disease

16Heart Failure
11/2010 - 09/2002
12Myocardial Infarction
04/2008 - 01/2002
8Cardiomegaly (Heart Hypertrophy)
11/2010 - 06/2003
4Hypertrophy
01/2010 - 01/2003
2Hypertension (High Blood Pressure)
01/2012 - 01/2007
2Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
07/2010 - 01/2003
2Infarction (Infarctions)
04/2008 - 01/2002
2Peripheral Vascular Diseases (Peripheral Vascular Disease)
04/2008 - 01/2004
1Hypercholesterolemia
01/2012
1Body Weight (Weight, Body)
09/2011
1Necrosis
07/2010
1Polyploidy
03/2010
1Retinoblastoma (Glioblastoma, Retinal)
01/2010
1Ventricular Tachycardia
01/2008
1Tachycardia (Tachyarrhythmias)
01/2008
1Ventricular Premature Complexes (Premature Ventricular Contraction)
01/2008
1Cardiac Arrhythmias (Arrythmia)
01/2008
1Coronary Occlusion
01/2008
1Myeloid Leukemia (Leukemia, Myelocytic)
05/2007
1Lymphoma (Lymphomas)
03/2007
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
03/2007
1Essential Hypertension
01/2007
1Fatigue
09/2005
1Multiple Organ Failure (MODS)
01/2005
1Hypovolemia
01/2005
1Shock
01/2005
1Endotoxemia
01/2005
1Cardiovascular Diseases (Cardiovascular Disease)
01/2004
1Pulmonary Hypertension
01/2004
1cyclopia sequence
11/2003

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
11/2010 - 12/2004
8imidaprilIBA
06/2005 - 07/2002
7Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
06/2005 - 07/2002
4sarpogrelateIBA
04/2008 - 01/2002
4Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
06/2005 - 07/2002
3Adenosine Triphosphatases (ATPase)IBA
06/2005 - 07/2002
2Antihypertensive Agents (Antihypertensives)IBA
01/2012 - 01/2007
2Cyclin D1IBA
11/2010 - 01/2010
2Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
04/2008 - 01/2008
2Type 3 Cyclic Nucleotide PhosphodiesterasesIBA
04/2008 - 01/2008
2Cilostazol (Pletal)FDA LinkGeneric
04/2008 - 01/2008
2Brain Natriuretic Peptide (Natrecor)FDA Link
04/2008 - 01/2007
2Fenofibrate (CiL)FDA LinkGeneric
04/2008 - 01/2008
2Serotonin (5 Hydroxytryptamine)IBA
09/2005 - 11/2003
2Angiotensin Receptor AntagonistsIBA
06/2005 - 06/2003
2Messenger RNA (mRNA)IBA
04/2005 - 12/2004
2Protein Isoforms (Isoforms)IBA
12/2004 - 06/2003
2Isoproterenol (Isoprenaline)FDA LinkGeneric
08/2004 - 08/2004
2Adrenergic Receptors (Adrenergic Receptor)IBA
08/2004 - 08/2004
2CatecholaminesIBA
08/2004 - 08/2004
1LipidsIBA
01/2012
1Rosuvastatin Calcium (Crestor)FDA Link
01/2012
1Triglycerides (Triacylglycerol)IBA
09/2011
1Insulin (Novolin)FDA Link
09/2011
1CholesterolIBA
09/2011
1Glucose (Dextrose)FDA LinkGeneric
09/2011
1SurvivinIBA
11/2010
1Apoptosis Regulatory ProteinsIBA
07/2010
1p38 Mitogen-Activated Protein KinasesIBA
07/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2010
1IsoenzymesIBA
07/2010
1DNA (Deoxyribonucleic Acid)IBA
03/2010
1Retinoblastoma ProteinIBA
01/2010
1Cell Cycle ProteinsIBA
01/2010
1E2F Transcription FactorsIBA
01/2010
1Chromogranin AIBA
04/2008
1Biomarkers (Surrogate Marker)IBA
04/2008
1Serotonin AntagonistsIBA
04/2008
1Natriuretic PeptidesIBA
04/2008
1Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
04/2008
1tryptamineIBA
01/2008
1Epinephrine (Adrenaline)FDA LinkGeneric
01/2008
1Rituximab (Mabthera)FDA Link
03/2007
1Immunoglobulins (Immunoglobulin)IBA
03/2007
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2007
1Factor V (Coagulation Factor V)IBA
09/2005
1Sodium-Calcium ExchangerIBA
06/2005
1Losartan (Cozaar)FDA LinkGeneric
06/2005
1CationsIBA
06/2005
1EnalaprilFDA LinkGeneric
06/2005
1Carrier Proteins (Binding Protein)IBA
04/2005
1Focal Adhesion Protein-Tyrosine KinasesIBA
01/2005
1PaxillinIBA
01/2005
1CalciumIBA
01/2005
1Adenosine Triphosphate (ATP)IBA
01/2005
1Vasoconstrictor AgentsIBA
01/2005
1Matrix Metalloproteinase 14 (MT1-MMP)IBA
01/2005
1Matrix Metalloproteinases (MMPs)IBA
01/2005
1endo-alpha-sialidaseIBA
01/2005
1norfenefrineIBA
01/2005
1Calcium-Transporting ATPases (Ca2+ ATPase)IBA
12/2004
1Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
12/2004
1CalsequestrinIBA
12/2004
1phospholambanIBA
12/2004
1ThapsigarginIBA
11/2003
1Diltiazem (Cardizem)FDA LinkGeneric
11/2003
1Verapamil (Calan)FDA LinkGeneric
11/2003

Therapy/Procedure

5Heart-Assist Devices
11/2010 - 08/2003
2Therapeutics
04/2008 - 01/2007
1Aftercare (After-Treatment)
03/2007